Jeffrey N Keller Selected Research

Hypoadiponectinemia

1/2016	Elevated adiponectin prevents HIV protease inhibitor toxicity and preserves cerebrovascular homeostasis in mice.
6/2014	Designer adiponectin receptor agonist stabilizes metabolic function and prevents brain injury caused by HIV protease inhibitors.
12/2010	Metabolic and neurologic consequences of chronic lopinavir/ritonavir administration to C57BL/6 mice.

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Jeffrey N Keller Research Topics

Disease

29	Alzheimer Disease (Alzheimer's Disease) 01/2020 - 06/2003
12	Cognitive Dysfunction 08/2020 - 05/2006
7	Neurodegenerative Diseases (Neurodegenerative Disease) 01/2019 - 04/2002
7	Obesity 01/2016 - 03/2012
6	Metabolic Syndrome (Dysmetabolic Syndrome X) 01/2016 - 12/2010
6	Inflammation (Inflammations) 02/2013 - 08/2004
5	Neurocognitive Disorders (Clerambault Syndrome) 01/2016 - 11/2010
5	Parkinson Disease (Parkinson's Disease) 01/2016 - 07/2003
4	Encephalitis (Encephalitis, Rasmussen) 01/2016 - 04/2005
4	Body Weight (Weight, Body) 01/2016 - 02/2004
4	Insulin Resistance 08/2012 - 12/2010
3	Hyperlipidemias (Hyperlipidemia) 01/2020 - 12/2010
3	Hyperinsulinism (Hyperinsulinemia) 01/2016 - 12/2010
3	HIV Infections (HIV Infection) 01/2016 - 02/2009
3	Neuroblastoma 01/2016 - 05/2008
3	Lipodystrophy 01/2016 - 12/2010
3	Hypoadiponectinemia 01/2016 - 12/2010
3	Brain Injuries (Brain Injury) 06/2014 - 09/2002
3	Gliosis 03/2012 - 09/2003
3	Mitochondrial Diseases (Mitochondrial Disease) 03/2006 - 05/2004
2	Hypertension (High Blood Pressure) 01/2020 - 11/2011
2	Dementia (Dementias) 01/2020 - 12/2011
2	Hypertriglyceridemia 01/2016 - 06/2014
2	Amyloid Plaque 10/2012 - 01/2012
2	Malnutrition (Nutritional Deficiencies) 06/2010 - 09/2008
2	Neoplasms (Cancer) 09/2009 - 11/2008
2	Pathologic Processes 02/2007 - 01/2007
2	Huntington Disease (Huntington's Disease) 04/2005 - 04/2002
1	Psychotic Disorders (Schizoaffective Disorder) 06/2020
1	Weight Loss (Weight Reduction) 01/2020
1	Type 2 Diabetes Mellitus (MODY) 01/2020
1	Morbid Obesity 01/2019
1	Neuroinflammatory Diseases 01/2016
1	Hyperglycemia 01/2016
1	Cerebral Amyloid Angiopathy (Congophilic Angiopathy) 12/2015
1	Epilepsy (Aura) 04/2013
1	Hypoxia (Hypoxemia) 10/2011
1	Disease Progression 06/2010

Drug/Important Bio-Agent (IBA)

13	Proteasome Endopeptidase Complex (Proteasome)IBA 01/2016 - 06/2003
13	Amyloid (Amyloid Fibrils)IBA 01/2016 - 03/2006
13	Proteins (Proteins, Gene)FDA Link 01/2012 - 04/2005
5	Reactive Oxygen Species (Oxygen Radicals)IBA 03/2013 - 01/2006
4	Glucose (Dextrose)FDA LinkGeneric 01/2019 - 10/2011
4	Peptides (Polypeptides)IBA 04/2013 - 12/2011
4	NADPH Oxidases (NAD(P)H oxidase)IBA 02/2013 - 02/2009
3	HIV Protease InhibitorsIBA 01/2016 - 07/2012
3	Ritonavir (Norvir)FDA Link 01/2016 - 12/2010
3	Lopinavir FDA Link 01/2016 - 12/2010
3	Free RadicalsIBA 12/2011 - 03/2003
3	Amyloid beta-PeptidesIBA 02/2009 - 03/2006
3	RNA (Ribonucleic Acid)IBA 06/2007 - 01/2006
2	CholesterolIBA 01/2019 - 01/2010
2	Protease Inhibitors (Protease Inhibitor)IBA 01/2016 - 12/2010
2	Peptide Hydrolases (Proteases)FDA Link 01/2016 - 09/2002
2	UbiquitinIBA 01/2016 - 01/2016
2	CarbohydratesIBA 01/2016 - 04/2013
2	LipidsIBA 01/2016 - 10/2011
2	Triglycerides (Triacylglycerol)IBA 06/2015 - 01/2012
2	Indicators and Reagents (Reagents)IBA 01/2014 - 01/2012
2	EnzymesIBA 02/2013 - 12/2011
2	4-hydroxy-2-nonenal (4-hydroxynonenal)IBA 01/2013 - 02/2004
2	2- (4'- (methylamino)phenyl)- 6- hydroxybenzothiazole (Pittsburgh compound B)IBA 10/2012 - 01/2012
2	Insulin (Novolin)FDA Link 08/2012 - 10/2011
2	Oxygen (Dioxygen)IBA 10/2011 - 08/2004
2	CytokinesIBA 02/2010 - 04/2005
2	Presenilin-1IBA 02/2009 - 03/2006
2	DNA (Deoxyribonucleic Acid)IBA 01/2006 - 02/2004
2	polyglutamineIBA 04/2005 - 04/2002
1	Opioid Analgesics (Opioids)IBA 06/2020
1	Apolipoprotein E4IBA 01/2020
1	Apolipoproteins E (ApoE)IBA 01/2020
1	TOR Serine-Threonine KinasesIBA 01/2019
1	Protein AggregatesIBA 01/2016
1	Rivastigmine (Exelon)FDA LinkGeneric 01/2016
1	Donepezil (Aricept)FDA LinkGeneric 01/2016
1	Glycine (Aminoacetic Acid)FDA LinkGeneric 01/2016
1	Hormones (Hormone)IBA 01/2016
1	Valine (L-Valine)FDA Link 01/2016
1	Member 1 Subfamily B ATP Binding Cassette TransporterIBA 01/2016
1	Plant LectinsIBA 01/2016
1	GhrelinIBA 01/2016
1	Olive OilIBA 11/2015
1	asparaginyl- isoleucyl- prolyl- norvalyl- leucyl- tyrosyl- seryl- phenylalanyl- alanyl- serinamideIBA 06/2014
1	AdiponectinIBA 06/2014
1	Adiponectin ReceptorsIBA 06/2014
1	Oxidoreductases (Dehydrogenase)IBA 02/2013
1	Fatty Acids (Saturated Fatty Acids)IBA 03/2012
1	Vasoconstrictor AgentsIBA 11/2011
1	Glutamic Acid (Glutamate)FDA Link 11/2010
1	NF-E2-Related Factor 2IBA 09/2010
1	AntioxidantsIBA 09/2010
1	Brain-Derived Neurotrophic Factor (BDNF)IBA 02/2010
1	Biomarkers (Surrogate Marker)IBA 02/2010

Therapy/Procedure

4	Therapeutics 01/2016 - 09/2009
1	Precision Medicine 08/2020
1	Polypharmacy 01/2020
1	Fat-Restricted Diet (Diet, Fat Restricted) 01/2016
1	Ketogenic Diet 04/2013
1	Highly Active Antiretroviral Therapy (HAART) 07/2012
1	Caloric Restriction 06/2010